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Psoralea corylifolia

Babachi botanically known as Psoralea corylifolia grows as weed. Since generations, it is in use as folk medicine in India . It is mainly used in treatment of leucoderma. In many parts of India , it is under cultivation as medicinal crop. According to Ayurveda, seeds are refrigerant, alternative, laxative, antipyretic, anthelmintic and good for heart troubles.

The monoterpenes and flavonoids isolated from the seeds of Psoralea corylifolia inhibited NADPH-, ascorbate-, t-BuOOH- and CCl (4)-induced lipid peroxidation in microsomes. They also prevented NADH-dependent and ascorbate-induced mitochondrial lipid peroxidation. They showed potent antioxidant activity in microsomes and the inhibition of oxygen consumption induced by lipid peroxidation was time-dependent. Furthermore, it protected human red blood cells against oxidative haemolysis. These phenolic compounds in Psoralea corylifolia were shown to be effective in protecting biological membranes against various oxidative stresses.

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