Tylophora asthmatica (syn. Tylophora indica) commonly known as Indian ipecac has its long-standing use as a folk remedy for asthma, and other respiratory problems like bronchitis, rheumatism, and dermatitis.

Tylophora asthmatica is clinically trialed in 110 bronchial asthma patients. After six days treatment, 62% of the patients consuming tylophora reported experiencing moderate to complete relief of their asthma symptoms compared to 28% in the placebo group. Moreover, when patients were switched from the placebo to the active group and vice versa, similar positive trends could be seen, with 50% of the tylophora group and 11% of the placebo group reporting symptomatic relief. In a follow-up study, the extract of Tylophora asthmatica leaves exhibited moderate to complete improvement in asthmatic symptoms in 56% of the patients compared to 32% in the placebo group.

In another study one group received either 350 mg of Tylophora leaf powder or placebo daily in the first week. A second group of asthmatics were given a similar amount of the leaf for seven days followed by an anti-asthmatic drug combination. Overall, results of the study showed the amount of oxygen in the lungs (e.g., vital capacity) increased in those using the leaf, but decreased in those using the placebo. In addition, those taking the herb had a notable nighttime reduction in their symptoms of shortness of breath.

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