Kutki botanically known as Picrorhiza kurroa is a small perennial herb from the Scrophulariaceae family, found in the Himalayan region. The name 'Kutki' seems to have been derived from the Sanskrit name 'Katuka', which means bitter taste. It is a well-known herb in the Ayurvedic system of medicine and has historically been used to treat disorders of the liver and upper respiratory tract, asthma, reduce fevers, and to treat dyspepsia, chronic diarrhea, and scorpion sting.

A trial was carried out using crude rhizome powder of Picrorrhiza kurroa as monotherapy in high doses on patients of obstructive airway diseases. A significant reduction in the global score of respiratory sign and symptoms was observed along with reductions in the eosinophil count of the blood. There was significant improvement in the respiratory functions and viscosity of the sputum decreased with one week of treatment. Preclinical studies also reported that Picrorrhiza kurroa prevented allergen- and platelet-activating factor-induced bronchial obstruction (10 mg/kg orally; 0.5 mg inhalative).

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