Tulsi indigenous plant of India botanically known as Ocimum sanctum has been used historically since the vedic period. Hindus regard it as an earthly manifestation of goddess Vrindavani, who is dear to Lord Vishnu. Holy basil has number of therapeutic applications. To mention few of them include stomachic, anthelmintic, antipyretic; useful in diseases of the heart and blood, asthma, bronchitis etc.

The anti-asthmatic activity of the extract of dried and fresh leaves, and the volatile and fixed oils of Ocimum sanctum was evaluated against histamine and acetylcholine-induced pre-convulsive dyspnea (PCD) in guinea pigs. The extract of fresh leaves, volatile oil extracted from fresh leaves and fixed oil from the seeds significantly protected the guinea pigs against histamine-and acetylcholine-induced PCD. These extracts also inhibited hind paw edema induced in rats by treatment with carrageenan, serotonin, histamine of PGE2.

The leaves of the Ocimum sanctum plant were tried in cases of bronchial asthma, the Ocimum sanctum was found to be highly efficacious.

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