Spiny fruits of Tribulus terrestris commonly known as Puncture vein is variable, prostrate annual herb commonly found throughout India. Gokhru is conventionally used in ayurvedic system of medicine as diuretic, antiurolithiatic, sexual tonic, painful micturition etc.

Traditional use of Tribulus terrestris in the Chinese and Indian systems of medicine for the treatment of various ailments and is popularly claimed to improve sexual functions in man which is now scientifically confirmed. Sexual behavior and intracavernous pressure were studied in both normal and castrated rats to further understand the role of Tribulus terrestris containing protodioscin as an aphrodisiac. There was an overall reduction in the sexual behavior parameters in the castrated groups of rats as reflected by decrease in mount and intromission frequencies (MF and IF) and increase in mount, intromission, ejaculation latencies (ML, IL, EL) as well as post-ejaculatory interval (PEI). Compared to the castrated control, treatment of castrated rats (with either testosterone or Tribulus terrestris extract) showed increase in prostate weight. There was also a mild to moderate improvement of the sexual behavior parameters as evidenced by increase in MF and IF; decrease in ML, IL and PEI. These results were statistically significant. It is concluded that Tribulus terrestris extract appears to possess aphrodisiac activity probably due to androgen increasing property of Tribulus terrestris.

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