Sweet Flag botanically known as Acorus calamus is a herb with creeping and aromatic rhizomes occurs throughout India at the waterside or close to marshes, often found with reed beds. Sweet flag name refers to its sweet scent.

Ayurvedic science has always propagated the use of Sweet Flag as effective treatment against a wide variety of illnesses. Acorus calamus is also found to possess anti-inflammatory activity, which is evident from a number of studies.

Preclinical studies reported that the extract of Acorus calamus at a dose of 400 mg/kg produced 41.2 percent inhibition of carrageenin induced inflammation in rat paw oedema. Extract of Acorus calamus rhizomes also exhibited significant anti-inflammatory effect in experimental animals like acute and chronic models which was observed to be well comparable with that of the reference drugs like hydrocortisone, phenylbutazone etc.

In another study for evaluating anti-inflammatory effect revealed that the oral administration the extract of Acorus calamus caused 45 percent inhibition of the carrageenin induced paw oedema, 13.6 percent inhibition of cotton pellet granuloma formation and 61 percent inhibition of croton oil granuloma pouch inflammatory response in rats.

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